Publication of MerckKGaA, Darmstadt, Germany. In the USA and Canada the subsidiaries of Merck KGaA, Darmstadt, Germany operate as EMD Serono in Healthcare, MilliporeSigma in Life Science and EMD Performance Materials. Outside of the United states and Canada to avoid any misconception of the reader of the publication certain logos, terms and business descriptions of the publication have been substituted or additional descriptions have been added. Publications on this homepage therefore, slightly deviate from the otherwise identical version of the publications provided outside of the United States and Canada.